Michael Antoni, Ph.D., University of Miami, Miami, Florida
Dr. Antoni has demonstrated the positive effects of participation in group cognitive behavioral stress management (CBSM) on quality of life, perceived stress, fatigue, memory, muscle pain and post-exertional malaise for CFS patients compared to those in a control condition. Many CFS patients are too debilitated to attend regular therapy sessions. Therefore, in the present study, he will test the physiological effects of a telephone-based cognitive behavioral stress management intervention to illuminate CFS patients neuroimmune mechanisms in relation to stress and stress management. The correlation of the neuroimmune parameters and the behavioral components promises to identify a biologically useful marker for CFS.
Autonomic Nervous System in Chronic Fatigue Syndrome
Italo Biaggioni, M.D., Vanderbilt University, Nashville, Tennessee
Dr. Biaggioni will explicate the role of the sympathetic nervous system (SNS) in the cardiovascular and inflammatory abnormalities in the subset of patients with postural tachycardia (POTS) increase in heart rate and often decrease in blood pressure on standing. Preliminary studies indicate a relationship between the mechanisms underlying POTS and CFS symptoms. Dr. Baggioni will test these hypotheses in a comprehensive set of experiments with appropriate controls.
Sources:
NIH-Funded CFS Research. National Institutes of Health, Office of Research on Womens Health.
NIH Announces Awards in Chronic Fatigue Syndrome Research. National Institutes of Health Press Release.
