Definition: A small peptide released upon stimulation in the nervous system and involved in regulation of the pain threshold. Increased levels of substance P increase the sensitivity of nerves to pain or heighten awareness of pain. People with fibromyalgia can have elevated levels of substance P.
Sources:
Dictionary.com Unabridged (v 1.1), Based on the Random House Unabridged Dictionary, © Random House, Inc. 2006 substance p
Regina P Gilliland, MD, Department of Internal Medicine; Division of Rehab Medicine, Mobile Infirmary Medical Center"Fibromyalgia"
