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CoQ10 Supplements for Fibromyalgia & Chronic Fatigue Syndrome


Updated June 25, 2014

CoQ10 & Energy:

CoQ10, or coenzyme Q10, is a powerful antioxidant that is in most of the tissues in your body. The role of coenzymes is to break down food and convert it to energy in the form of adenosine triphosphate (ATP), which studies show is sometimes deficient in people with fibromyalgia and chronic fatigue syndrome.

CoQ10 Dosage:

A typical dosage of CoQ10 is 30 to 90 mg each day, taken in smaller doses 2 or 3 times a day. Some doctors recommended as much as 200 mg per day. So far, there's no specific dosage recommendation for fibromyalgia or chronic fatigue syndrome.

CoQ10 is fat-soluble, which means that you'll absorb it better when you take it with a meal containing oil or fat.

CoQ10 works slowly, so you may not see any therapeutic benefit for up to 8 weeks. While early studies on CoQ10 for these conditions are promising, more research needs to be done.

Before starting any supplement, of course, you should consult your doctor.

CoQ10 In Your Diet:

You can get more CoQ10 in your diet by eating more oily fish, organ meats and whole grains. It's widely available in supplement form.

Adding Fish to Your Diet:

CoQ10 Side Effects:

Some people do experience negative side effects of CoQ10, but these effects typically are mild and do not require treatment.

Side effects include:

  • Nausea and/or vomiting
  • Heartburn
  • Diarrhea
  • Loss of appetite
  • Skin itching
  • Rash
  • Insomnia
  • Headache
  • Dizziness
  • Itching
  • Irritability
  • Increased light sensitivity of the eyes
  • Fatigue
  • Flu-like symptoms

Caution: CoQ10 may lower blood sugar levels and blood pressure. If you have diabetes, hypoglycemia or low blood pressure, be sure to talk to your doctor before starting CoQ10 supplements.

More Supplement Information


Alternative Medicine Review. 2000 Apr;5(2):93-108. "Nutritional strategies for treating chronic fatigue syndrome."

Journal of International Medical Research. 2002 Mar-Apr;30(2):195-9. "An open, pilot study to evaluate the potential benefits of coenzyme Q10 combined with Ginkgo biloba extract in fibromyalgia syndrome."

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