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Post-Exertional Malaise


Updated June 20, 2014


Malaise is a vague feeling of body discomfort or a general feeling of being unwell, much like you feel when you're coming down with a cold or the flu.

Post-exertional malaise is a period of intense exhaustion and other ME/CFS symptoms that lasts for more than 24 hours following physical exertion. This symptom is a hallmark of chronic fatigue syndrome (CFS or ME/CFS) and causes detectable differences in the blood that are being studied as a possible diagnostic marker.

Also Known As: Post-Exertion Malaise
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