Researches say the drug appeared to improve the amount of restorative sleep participants got each night. They also say they may have discovered a biomarker to assess the effect of treatment on non-restorative sleep as well as the fatigue and mood symptoms that stem from it.
Cyclobenzaprine is in the brand-name drugs Flexeril and Cycloflex. It's a common muscle relaxer, but it's also closely related to tricyclic antidepressants. The typical dosage range is 5-10 mg, 3 times a day. In this study, participants too a gradually increasing dosage starting at 1 mg and ending with 4 mg, only at bedtime.
Researchers say the drug was well tolerated and no serious side effects or discontinuation problems were reported.
You can find a side-effects list and other information on this drug here: Cyclobenzaprine.
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